Cytopathology of Extra-genital Transmissible Venereal Tumour in a dog in Lusaka, Zambia

  • Girja Shanker Pandey
  • Careen Hankanga University of Zambia
  • Farai Phiri
  • Mercy Mfula Chipolo Department of Clinical Studies, School of Veterinary Medicine, University of Zambia
  • Racheal Mwenda
  • Noanga Mebelo
Keywords: Extra-genital TVT, dog, haemato-biochemistry, cytopathology, diagnosis, Zambia

Abstract

Transmissible Venereal Tumour (TVT) a round cell tumours probably originating from genetic alteration of canine histiocytes is horizontally and sexually transmitted that affects dogs and other canids. There is no published report on extra-genital TVT among dogs in Zambia. The present case reports the cytopathology and haemato-biochemistry of an extra-genital TVT, without primary genital involvement in a 4 year old male dog in Lusaka, Zambia. There were a total of 18 cutaneous immobile nodules ranging in size from 25 to 57 mm on the dorsal and ventral aspect of the body and no ulceration or bleeding was observed. Haemato-biochemstry revealed anaemia, thrombocytopaenia, hyperproteinaemia, increased blood creatinine and urea nitrogen. Based on cytology, TVT of lymphoid sub type was diagnosed ruling out suspicion of cutaneous lymphoma or histiocytoma. Definitive diagnosis was easily based on physical examination and cytological findings of typical of TVT cells in exfoliated cells through FNAC which is rapid, reliable, efficient, cost favourable and more conclusive hastening intervention than waiting for histopathology. Our findings emphasize the need to consider TVT on the list of differential diagnosis for masses in extragenital sites in dogs from geographic regions where TVT is prevalent.

Author Biographies

Girja Shanker Pandey
Professor, Department of Disease Control, School of Veterinary Medicine, University of Zambia
Careen Hankanga, University of Zambia
Senior Lecturer, Department of Clinical Studies, School of Veterinary Medicine, University of Zambia
Farai Phiri
Clinic Manager, Department of Clinical Studies, School of Veterinary Medicine, University of Zambia
Mercy Mfula Chipolo, Department of Clinical Studies, School of Veterinary Medicine, University of Zambia
House Surgeon, Department of Clinical Studies, School of Veterinary Medicine, University of zambia
Racheal Mwenda
Lecturer, Department of Paraclinical Studies, School of Veterinary Medicine, University of Zambia
Noanga Mebelo
House Surgeon. Department of Paraclinical Studies, School of Veterinary Medicine, University of Zambia

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Published
2023-11-24
How to Cite
1.
Pandey G, Hankanga C, Phiri F, Chipolo M, Mwenda R, Mebelo N. Cytopathology of Extra-genital Transmissible Venereal Tumour in a dog in Lusaka, Zambia. University of Zambia Journal of Agricultural and Biomedical Sciences [Internet]. 24Nov.2023 [cited 16Apr.2024];7(1). Available from: https://journals.unza.zm/index.php/JABS/article/view/1093
Section
Veterinary Medicine